Immune System News

May 13, 2024

Top Headlines

Birth by C-Section More Than Doubles Odds of Measles Vaccine Failure

May 13, 2024 — Birth by C-section more than doubles odds of measles vaccine failure. Researchers say it is vital that children born by caesarean section receive two doses of the measles vaccine for robust protection against the ...

Plant Virus Treatment Shows Promise in Fighting Metastatic Cancers in Mice

May 13, 2024 — An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study. The treatment, composed of nanoparticles fashioned from the cowpea mosaic virus -- a virus that ...

New Vaccine Effective Against Coronaviruses That Haven't Even Emerged Yet

May 6, 2024 — Researchers have developed a new vaccine technology that has been shown in mice to provide protection against a broad range of coronaviruses with potential for future disease outbreaks -- including ones we don't even know ...

GPS-Like System Shows Promise as HIV Vaccine Strategy to Elicit Critical Antibodies

May 9, 2024 — A team has developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against ...

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Direct Measurement of the Interaction Between Immune Cells and Cancer Cells from a Patient's Biopsy

May 6, 2024 — Researchers have unveiled a technology that promises to improve cancer treatment decisions based on a patient's biopsy. The pioneering biological ...

New Treatment Could Reverse Hair Loss Caused by an Autoimmune Skin Disease

May 9, 2024 — Researchers developed a potential new treatment for alopecia areata, an autoimmune disorder that causes hair loss. The microneedle patch delivers immune-regulating molecules that can teach T cells ...

A Tailored Vaccine Could One Day Treat Eczema in Children

May 8, 2024 — New research suggests a 'tailored vaccine' might hold the key to treating bacteria-driven flares of eczema in children. The team has taken several leaps forward in understanding how the immune ...

Children Sleep Problems Associated With Psychosis in Young Adults

May 8, 2024 — Children who experience chronic lack of sleep from infancy may be at increased risk of developing psychosis in early adulthood, new research ...

Strengthening CAR-T Therapy to Work Against Solid Tumors

May 8, 2024 — Researchers have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors -- an advance that could transform cancer treatment. The promising findings involve ...

AI Predicts Tumor-Killing Cells With High Accuracy

May 7, 2024 — Using artificial intelligence, scientists have developed a powerful predictive model for identifying the most potent cancer killing immune cells for use in cancer ...

New Strategy Could Lead to Universal, Long-Lasting Flu Shot

May 1, 2024 — An experimental influenza vaccine carrying more than 80,000 variations of hemagglutinin antigens caused the immune system of mice and ferrets to respond more strongly to less variable portions of the ...

Expanding a Lymph Node, Boosting a Vaccine

May 6, 2024 — Researchers have found a way to enhance and extend LN expansion, and study how this phenomenon affects both the immune system and efficacy of vaccinations against tumors. While the oversized LNs ...

New Immunosuppressive Mechanism Found in Brain Cancer

May 3, 2024 — Scientists have discovered how glioblastoma evades the immune system by inducing pro-tumor macrophages via a glucose based epigenetic ...

Source of Pregnancy Complications from Infections Revealed by Placenta Map

May 3, 2024 — The placenta's response to infections from malaria, toxoplasmosis and listeria has been mapped in high resolution, possibly paving the way for new treatment ...

Newly Discovered Mechanism of T-Cell Control Can Interfere With Cancer Immunotherapies

May 3, 2024 — Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body presumably curbs ...

Activation of Innate Immunity: Important Piece of the Puzzle Identified

May 2, 2024 — Researchers have deciphered the complex interplay of various enzymes around the innate immune receptor toll-like receptor 7 (TLR7), which plays an important role in defending our bodies against ...

Gene Signatures from Tissue-Resident T Cells as a Predictive Tool for Melanoma Patients

May 2, 2024 — A new study has revealed an association between favorable survival outcomes for melanoma patients and the presence of higher populations of tissue-resident memory T cells (TRM). Data obtained from ...

Scientists Identify New Brain Circuit in Mice That Controls Body's Inflammatory Reactions

May 1, 2024 — The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in ...

New mRNA Cancer Vaccine Triggers Fierce Immune Response to Fight Malignant Brain Tumor

May 1, 2024 — An mRNA cancer vaccine quickly reprogrammed the immune system to attack the most aggressive type of brain tumor in a first-ever human clinical ...

Regulating Cholesterol Levels Might Be the Key to Improving Cancer Treatment

Apr. 30, 2024 — Researchers have identified a mechanism that can improve current immunotherapies by regulating cholesterol levels. The study shows the potential of manipulating cholesterol levels in future treatment ...

Experimental Type 1 Diabetes Drug Shelters Pancreas Cells from Immune System Attack

Apr. 29, 2024 — Scientists say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the ...

Component of Keto Diet Plus Immunotherapy May Reduce Prostate Cancer

Apr. 26, 2024 — Adding a pre-ketone supplement -- a component of a high-fat, low-carb ketogenic diet -- to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, ...

Pregnancy Cytokine Levels Impact Fetal Brain Development and Offspring Behavior

Apr. 26, 2024 — Researchers have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for ...

Vitamin D Alters Mouse Gut Bacteria to Give Better Cancer Immunity

Apr. 25, 2024 — Researchers have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to ...

How Immune Cells Communicate to Fight Viruses

Apr. 25, 2024 — Chemokines are signalling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to ...

Tumor Cells Evade the Immune System Early On: Newly Discovered Mechanism Could Significantly Improve Cancer Immunotherapies

Apr. 24, 2024 — Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers have now uncovered for the first time how this exactly ...

Ready and Vigilant: Immune Cells on Standby

Apr. 24, 2024 — When pathogens invade the body, the immune system must react immediately to prevent or contain an infection. But how do our defence cells stay ready when no attacker is in sight? Scientists have ...

Apply Single-Cell Analysis to Reveal Mechanisms of a Common Complication of Crohn's Disease

Apr. 24, 2024 — Study identifies key pathways underlying perianal fistula, a disease complication that is more prevalent and severe in African American ...

The Enemy Within: How Pathogens Spread Unrecognized in the Body

Apr. 22, 2024 — Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In ...

Genetically Engineering a Treatment for Incurable Brain Tumors

Apr. 22, 2024 — Scientists are developing and validating a patent-pending novel immunotherapy to be used against glioblastoma brain tumors. Glioblastomas are almost always lethal with a median survival time of 14 ...

Researchers Develop a New Way to Safely Boost Immune Cells to Fight Cancer

Apr. 19, 2024 — Researchers explore a cancer immunotherapy treatment that involves activating the immune cells in the body and reprogramming them to attack and destroy cancer cells. This therapeutic method ...

Signs of Multiple Sclerosis Show Up in Blood Years Before Symptoms

Apr. 19, 2024 — In a discovery that could hasten treatment for patients with multiple sclerosis (MS), scientists have discovered a harbinger in the blood of some people who later went on to develop the ...

Study Opens New Avenue for Immunotherapy Drug Development

Apr. 19, 2024 — Researchers have designed a new method for developing immunotherapy drugs using engineered peptides to elicit a natural immune response inside the ...

COVID-19 Booster Immunity Lasts Much Longer Than Primary Series Alone, Study Shows

Apr. 18, 2024 — A new study shows that immunity after a COVID-19 booster lasts much longer than the primary series alone. These findings are among other, sometimes 'unintuitive,' revelations of how factors ...